The term developmental disabilities (DD) refers to people with intellectual disability, autism spectrum, fetal alcohol spectrum and related neurodevelopmental genetic syndromes. Children, youth, and adults with DD are vulnerable to high rates of general health and mental health concerns. This interactive 2020 conference will focus on practical strategies to optimize the quality of life for people with DD. Our goal is to help clinicians and caregivers learn effective ways to work with people with DD, and their families, in partnership to improve their quality of life experience. The conference will also provide educational and informative psychiatric, behavioural, mental health, and complex physical health updates specific to people with DD, and showcase best practices in the field. This conference will engage health care providers and educators from a wide range of professional disciplines in knowledge transfer and interdisciplinary collaboration.